Pemanfaatan Ekstrak Daun Katuk Sauropus Androgynus (L) Merr Dalam Formulasi Sediaan Mikropartikulat Dengan Metode Ekstrusi Sferonisasi
نویسندگان
چکیده
Pelet merupakan sistem multipartikulat yang memiliki distribusi ukuran partikel 0,5 – 1,5 mm denganmetode ekstrusi sferonisasi. Keunggulan pelet adalah sifat alir baik, dan porositas rendah.Sediaan akan dibuat minuman dengan bahan dasar ekstrak katuk. Katuk (Suaropus androgynus L)umum dikonsumsi masyarakat sebagai sayuran, karena bermanfaat laktagoga atau pelancar ASI.Pembuatan katuk PVP K30, sukralos, avicel pH 102. Penelitian inidilakukan untuk membuat memanfaatkan teknologi tepat guna ekstruder, sferoniser,dan coater. ini dilakukan beberapa tahapan antara lain pengumpulan bahan, penapisan fitokimia,optimasi pengikat, pembuatan ekstrak, penyalutan. Evaluasi terhadap lainlaju alir, susut pengeringan, sudut istirahat, partikel, uji waktu melarut, volumesedimentasi, kenaikan bobot, hedonik. Hasil evaluasi optimasi pengikat (PVP K30) didapatkanformula terbaik 5%, sukralos 0,20%, 102 94,80%. hedonik menunjukanformula salut disukai oleh panelis formula 6P konsentrasi pvp5%, 89,80%. Dapat disimpulkan bahwa teknologiekstrusi, sferonisasi dapat digunakan dalam salut.
منابع مشابه
Sauropus androgynus (L.) Merr. Induced Bronchiolitis Obliterans: From Botanical Studies to Toxicology
Sauropus androgynus L. Merr. is one of the most popular herbs in South Asia, Southeast Asia, and China where it was known as a slimming agent until two outbreaks of pulmonary dysfunction were reported in Taiwan and Japan in 1995 and 2005, respectively. Several studies described that the excessive consumption of Sauropus androgynus could cause drowsiness, constipation, and bronchiolitis oblitera...
متن کاملPhytochemical Analysis and GC-MS profiling in the leaves of Sauropus Androgynus (l) MERR
In the present the phytochemical analysis of Sauropus androgynus was carried out. Phytochemical analysis of the leaves of this plant is reported for the first time. The leaves indicated the presence of proteins, resins, steroids, tannins, glycosides, reducing sugar, carbohydrates, saponins, sterols, terpenoids, acidic compounds, cardiac glycosides, catechol, phenols, alkaloids, flavonoids. In t...
متن کاملBronchiolitis Obliterans Organizing Pneumonia Following Consumption of Sauropus androgynus
Bronchiolitis obliterans organizing pneumonia (BOOP) is a rare disorder affecting the small airways, alveoli and the walls of small bronchi. This form of lung injury involves inflammation and stiffening of lung areas with organized tissue. There are several known causes of BOOP, and several systemic disorders have BOOP as an associated primary pulmonary lesion. An outbreak of BOOP among young w...
متن کاملComparisons of Curative Effects of Chlorophyll from Sauropus androgynus (L) Merr Leaf Extract and Cu-Chlorophyllin on Sodium Nitrate-Induced Oxidative Stress in Rats
Sodium nitrate (NaNO2) widely used as food additive for coloring and preserving meat has been reported to induce oxidative stress and cause histopathologic changes, nitrosative tissue damage, and lipid peroxidation in liver and kidney. Therefore, the present study compared the curative effect of chlorophyll from Sauropus androgynus (L) Merr and Cu-chlorophyllin as antioxidant in NaNO2-induced f...
متن کاملAqueous fraction of Sauropus androgynus might be responsible for bronchiolitis obliterans.
BACKGROUND AND OBJECTIVE Bronchiolitis obliterans (BO) has been reported to develop following ingestion of Sauropus androgynus (SA), a leafy shrub distributed in Southeast Asia. Little is known about direct effects of SA on airway resident cells or haematopoietic cells in vitro. Identification of the SA component responsible for the development of BO would be an important key to elucidate its m...
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ژورنال
عنوان ژورنال: IKRA-ITH teknologi
سال: 2022
ISSN: ['2654-8046', '2580-4308']
DOI: https://doi.org/10.37817/ikraith-teknologi.v6i3.2310